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What is Ozone Therapy?
Ozone therapy has been used in clinical medicine across Europe for over 60 years.
It works by introducing O₃ — a molecule made of three oxygen atoms — into the body at precise, measured concentrations.
It doesn't act on the body directly. It acts as a trigger, setting off a cascade your body carries out itself:
Stimulates mitochondrial energy production — supporting how efficiently your cells actually perform
Modulates immune function — helping your body respond more effectively to what it's dealing with
Improves how efficiently your blood delivers oxygen to the tissues that need it
Helps address the low-grade inflammation that builds quietly under sustained pressure
At Your Little Self, treatment is delivered by a Registered Nurse in a quiet, private clinic in Kensal Rise, NW10 — under CQC governance, with the clinical precision the therapy demands.
Energy & fatigue
Chronic tiredness isn't always about sleep. Often it's about how efficiently your cells are making energy in the first place. Ozone works at that level — supporting mitochondrial function, the part of the cell actually responsible for producing fuel. Many clients notice a shift in energy and mental clarity within the first few sessions.
[Read the research on ozone and energy →]
What Ozone Therapy Can Support.
Inflammation & recovery
The inflammation that causes the most long-term damage is usually the kind you can't feel — the low-grade, background kind that quietly shapes how your body ages and recovers. There's solid clinical evidence behind ozone's effect here, particularly for joint and muscle recovery.
[Read the research on ozone and inflammation →]
Skin & wound support
This is the one area where the evidence doesn't need much translating — wound healing is one of ozone's most clinically established applications.
[Read the research on ozone and skin health →]
Immune resilience
"Boosting" your immune system isn't really the goal — an immune system running too hot causes as many problems as one running too low. Ozone works by modulating that response, not simply cranking it up, which is why it's often used to support the body through periods of high demand: travel, seasonal changes, recovery from being run down.
[Read the research on ozone and immune function →]
Circulation & oxygen delivery
You're probably not short of oxygen — you're short of oxygen getting to where it's actually needed. That distinction matters: ozone improves the efficiency of delivery, not just the supply, which is why it's often used alongside training and recovery protocols.
[Read the research on ozone and circulation →]
Ozone therapy is a complementary therapy. It isn't a replacement for medical diagnosis or treatment — if you're managing an existing health condition, we'll talk through what's appropriate for you at your consultation.
How IV Ozone Therapy Works.
Also known as major autohemotherapy (MAH), IV ozone therapy is one of our most requested treatments. Here's what a session actually involves, step by step:
Blood collection. A measured quantity of your blood is drawn into a closed, sterile system.
Ozone infusion. Your blood is mixed with a precise ozone-oxygen concentration.
Reinfusion. The ozonated blood is returned to your body, carrying that oxygen throughout your system.
What's a "pass"?
Steps 2 and 3 together make up one pass. A session typically involves multiple passes — the same cycle repeated in sequence, rather than a different treatment. More passes means greater total ozone exposure within a single session; how many is right for you depends on your health history and what we're working towards, which we'll talk through at your consultation.
You're monitored by a Registered Nurse at every stage, so the process stays comfortable and safe from start to finish.
The result isn't a quick lift. It's a shift in how your body performs — in energy, mental clarity, recovery, and resilience.
Ozone Therapy Options at Your Little Self
5 Pass
Best for those with a complex health history or reduced detox capacity — a more gradual introduction where that's clinically appropriate.
Duration: around 45 minutes
We offer several ozone therapy formats, each suited to different needs and experience levels.
IV Ozone Therapy (Major Autohemotherapy)
10 Pass
A well-supported starting point for most — general fatigue, immune support.
Duration: around 1.5 hours
20 pass
Established clients, chronic fatigue that hasn't shifted with lower doses, deeper systemic support.
Duration: around 2 hours
The right pass count depends on your health history, not just preference — that's exactly what your consultation is for.
Rectal &/or Vaginal Insufflation
Delivered directly to mucosal tissue rather than into the bloodstream, this route allows for local, targeted absorption without a needle.
Rectally, that means direct contact with the gut lining and the microbial environment there — an area increasingly linked to digestion, immune regulation, and low-grade inflammation more broadly, not just gut symptoms in isolation.
Vaginally, the same local-delivery principle applies to vaginal tissue and its microbiome, supporting a healthy local environment.
Duration: around 20 minutes
Insufflation Therapy
Nasal Insufflation
Delivered directly to the nasal mucosa — one of the body's main points of contact with the air you breathe — this is the most localised of the formats we offer.
Because that tissue sits right at the entry point for airborne particles, applying ozone there brings it into direct contact with the nasal and sinus lining, supporting the local tissue environment and the immune activity concentrated in that area.
Duration: around 15 minutes
Ozone Therapy: Your Questions Answered
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Ozone therapy supports a range of wellness goals. People typically explore ozone treatment for:
Chronic fatigue and low energy — ozone is thought to support mitochondrial function and ATP production, the energy currency of your cells
Immune system support — ozone has been shown to modulate immune cell activity in laboratory studies, helping the immune system respond more effectively
Recovery and circulation — improved oxygen delivery to tissues supports healing and performance
General wellness optimisation — you don't need to be unwell to benefit; ozone therapy is also used preventively
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Pre-treatment screening matters. Certain conditions make ozone therapy, or the heparin used to support blood flow during treatment, unsuitable. This includes:
G6PD deficiency (a genetic enzyme condition) — ozone can trigger red blood cell breakdown in people with this condition
Untreated or unstable hyperthyroidism
A low platelet count, or other significant clotting disorders
Active bleeding, or a bleeding disorder such as haemophilia
Pregnancy or breastfeeding
A recent heart attack, or significant cardiovascular instability
Known sensitivity to heparin, or a history of heparin-induced thrombocytopenia
Current blood-thinning medication (such as warfarin or DOACs) — this needs review before treatment
Acute alcohol intoxication
Nothing on this list is assumed from a form. Every client goes through a full health history and consultation before treatment, so anything here — or anything you're unsure about — is properly assessed, not guessed at.
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When administered by trained clinicians following sterile, closed-system protocols, and with proper pre-treatment screening, ozone therapy is generally well tolerated. The most common experience is mild discomfort at the cannulation site.
Some clients notice flu-like symptoms — tiredness, mild aches, or a headache — in the day or so following treatment. This isn't universal, and for most people it passes on its own. If anything feels concerning or doesn't settle, get in touch — we'd always rather you check in than assume it's expected.
Ozone therapy is designed to work alongside your existing medical care, not replace it. We'd never recommend stepping away from your doctor's advice, and any changes to prescribed medication should always be discussed with your healthcare provider first.
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Your Consultation
Every ozone therapy journey starts with a consultation. We review your health history, current concerns, and wellness goals to build a protocol around you — not a generic menu.Your Session
A quiet, private treatment room in Kensal Rise, NW10
A full explanation of the process before we begin
Continuous monitoring by a Registered Nurse throughout your session
Clear aftercare guidance tailored to you — and an open line if anything feels off afterwards
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Many clients combine ozone therapy with IV supplementation — curcumin, or a triple-action blend of Vitamin C, Glutathione, and Acetylcysteine — for a more complete reset. This isn't required, but ozone works at a cellular level to address oxidative stress, while IV nutrients support detoxification and healing.
You can also combine IV ozone with insufflation in the same appointment. Many clients choose rectal or vaginal insufflation immediately following IV ozone therapy for for more targeted digestive or local support.
Book Your Ozone Therapy Consultation — Kensal Rise
Delivered by a Registered Nurse, under CQC governance, with the clinical precision the therapy demands.